His classical career was put on hold after a trip to New York in 1966 exposed him to emerging musical forms and ideas that led to him forming CAN in 1968. As the band's keyboard player, Schmidt’s contribution to their groundbreaking career and the evolution of electronic music in general is formidable. When CAN was dissolved in 1978, Schmidt relocated to the south of France where he established a studio and continued to compose and record over 100 film and television scores, a craft he had already become familiar with both before and during his work with CAN. This work is documented on CAN’s “Soundtracks” LP (1970) and on his own solo soundtrack compilation, a 3 CD set entitled “Anthology :Soundtracks 1978-1993“ both of which are available on Spoon /Mute. His solo soundtrack features his fellow band mates Michael Karoli (guitar) and Jaki Liebezeit (drums).
In 1981 he worked with Bruno Spoerri and released his first solo LP “Toy Planet” followed by “Musk at Dusk” in 1987. Schmidt rejoined his former colleagues for the reunion album, ”Rite Time” (1989) and followed this with another solo album,”Impossible Holidays” (1991).
In 1993, Schmidt was commissioned to write a fantasy opera based on Mervyn Peake's Gormenghast trilogy. The three act opera, with a libretto by Duncan Fallowell, was premiered at Wuppertal Opera House on November 15 1998 excerpts of which were released as a CD on Spoon/Mute in 2000
Thanks to Gormenghast, he met Kumo (UK musician Jono Podmore), sound engineer, producer and specialist in rhythm programming and immediately saw the potential for improvisational collaboration. They performed as Irmin Schmidt and Kumo for the Can solo projects tour. This project also toured events as diverse as the Montreux Jazz Festival, Sonar in Barcelona and the International Jazz festival in London and all to critical acclaim from their respective audiences. In 2001 Irmin Schmidt and Kumo released “Masters of Confusion” on Spoon/Mute.
Like his fellow CAN bandmates, Irmin Schmidt has been taking a keen interest in the re-mastering of CAN material for both the 2003 CAN DVD release and overseeing the re-mastering of the entire CAN back catalogue in 2004-2005 for a re-release on Spoon/Mute.
June 2004 saw a new production of his Gormenghast opera staged at Völklinger Hütte in Saarbrüken, Germany, a colossal steelworks that is now a UNESCO world heritage site, together with performances at the Grand Théatre Luxembourg.
In 2006 – 2007 he composed ballet music for full orchestra commissioned by the DEUTSCHEN OPER AM RHEIN, Düsseldorf. In 2008 the ballet was premiered in Düsseldorf and Duisburg. This year also saw the release of the new Irmin Schmidt & Kumo album Axolotl Eyes (released world wide by Spoon/Mute/Warner/P-Vine) and he wrote the soundtrack to the new Wim Wenders film Palermo Shooting, which is part of the official selection of the Cannes Film Festival 2008.